B-Form Helix AP Biology NCERT Grade 12
Bond View
Tap Coding / Non-Template Strand
10.5bp / turn
34 Åpitch
3.4 Årise / bp
5′
3′
3′
5′
5′→3′ Backbone
3′→5′ Backbone
DNA: A – T (2 H-bonds)
mRNA: A – U (2 H-bonds)
DNA: G – C (3 H-bonds)
mRNA: G – C (3 H-bonds)
Structure
🧬 Double Helix
DNA is a right-handed double helix — two antiparallel strands wound around a central axis like a twisted ladder. Discovered by Watson & Crick in 1953 using Franklin's X-ray data.
Antiparallel Strands
One strand runs 5′ → 3′ and the complementary strand runs 3′ → 5′. They always run in opposite directions — this is essential for DNA replication and transcription.
🔗 Base Pairing Rules
Only specific bases can pair (complementary base pairing):
Adenine (A) Thymine (T) ·· 2 H-bonds
Guanine (G) Cytosine (C) ··· 3 H-bonds
Chargaff's Rule
In any DNA sample: %A = %T and %G = %C. The ratio of purines to pyrimidines is always exactly 1:1.
Purine vs Pyrimidine
Purine
Adenine & Guanine
double ring structure
Pyrimidine
Thymine & Cytosine
single ring structure